" Role of Diffusion Weighted Image in the Diagnosis and Follow up of Breast Cancer"
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 主要终点
- Rate of correlated false positive results of MRI DWI for the lesion with the positive results by histopathology.
研究概览
简要总结
Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.
详细描述
Most of the lesions that occur in the breast are benign lesions. It is important to recognize benign lesions and distinguish them from breast cancer.
Nowadays sonomammography still represents the primary imaging modality utilized for breast cancer screening and diagnosis.
Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.Diffusion weighted imaging provides micro-structural informations regadrding the diffusion of the water molecules in the tissue cellularity and tissue structure by using the quantitive analysis with the apparent diffusion coefficient (ADC) values.
Using Diffusion weighted imaging (DWI) combined to MRI is helpful to distinguish malignant versus benign breast lesions and it also may reduce the number of unnecessarily breast biopsies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •* Female gender
- •Age more than 18 years
- •Patients presented with breast lump
- •Patients with recurrent breast cancer following chemotherapy or radiotherapy sessions.
排除标准
- •Male gender
- •Age younger than 18 years
- •Patients with recent breast trauma in the same diseased breast within the last 6 months
- •Lactating female presented with acute symptoms as trauma or breast abscess
- •Contraindication to perform MRI examination .these include : Cardiac pacemaker -Metallic aneurysm clips
结局指标
主要结局
Rate of correlated false positive results of MRI DWI for the lesion with the positive results by histopathology.
时间窗: 6 months
evaluation of the lesion with MRI DWI and histopathology for detect rate of false posive results
次要结局
未报告次要终点
研究者
Mennatallah Ashraf Ibrahim
Resident-radiology department-sohag hospital university
Sohag University