NCT00487643已完成不适用
Normal Lacritin Levels in Human Tears- Development of a New Clinical Assay
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- lacritin levels in human tears
研究概览
简要总结
Purpose: to build a library of normal tear lacritin values by collecting tears from normal adult human subjects and to develop a non-invasive clinical assay for lacritin. Such an assay will provide more sensitive indicators of eye disease for clinicians and determine if a particular therapy, such as recombinant lacritin drops, is of benefit.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Military health care beneficiary between the ages of 21-
- •Male or female, of any race, and at least 21 years old and not older than 55 years old at the time of tear collection.
- •Appropriately aged individuals who report that their eyes are "normal" and who have no active eye illness as determined by principal investigator or sub-investigator.
- •Ability and willingness to understand and provide informed consent to participate in this study.
排除标准
- •Irritated eye reflected by patient statements or finding of "red" eye.
- •Individuals with any infections or inflammatory ocular condition (e.g. have "pink eye" or uveitis).
- •Individuals diagnosed with dry eye or other ocular surface condition, including but not restricted to neurotrophic keratitis, anterior basement membrane dystrophy, and recurrent corneal erosions.
- •Individuals who are on any topical eye medications.
- •Anyone who reports previous reaction or the possibility of an allergic reaction to 0.5% proparacaine.
结局指标
主要结局
lacritin levels in human tears
时间窗: 2 minutes after instilling anesthetic eyedrop
次要结局
未报告次要终点
研究者
Samantha B. Rodgers, MD
Assistant Director, Warfighter Refractive Eye Surgery Program and Research Center at FT Belvoir
Fort Belvoir Community Hospital
研究点 (1)
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