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Effect of L-carnitine on COVID-19

Phase 3
Conditions
Condition 1: Acute respiratory infection caused by coronavirus. Condition 2: Acute respiratory infection caused by coronavirus.
COVID-19, virus not identified
COVID-19, virus identified
U07.2
U07.1
Registration Number
IRCT20151108024938N3
Lead Sponsor
Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
42
Inclusion Criteria

All patients COVID-19, admitted to intensive care unit
Age 18-65 years old
Satisfaction to participate in the study

Exclusion Criteria

Covid-19 with mold diarrhea
History of L-carnitine allergy
Use of anticonvulsant drugs
Hemodialysis

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ventilator dependence. Timepoint: Before and 7 days after intervention. Method of measurement: Using ABG and the opinion of an anesthesiologist.;C-reactive protein (CRP). Timepoint: Before and 7 days after intervention. Method of measurement: Quantitative method, by ELISA method.
Secondary Outcome Measures
NameTimeMethod
Mortality within the intensive care unit. Timepoint: Before intervention and 7 days after intervention. Method of measurement: Observe the occurrence.;The ratio of neutrophils to lymphocytes. Timepoint: Before intervention and 7 days after intervention. Method of measurement: Using a complete blood test.;Blood levels of lactate dehydrogenase. Timepoint: Before intervention and 7 days after intervention. Method of measurement: Enzymatic method.;The incidence of sepsis. Timepoint: Before intervention and 7 days after intervention. Method of measurement: Based on the diagnosis of the treating physician and SIRS criteria.;The incidence of respiratory distress. Timepoint: Before intervention and 7 days after intervention. Method of measurement: Based on the diagnosis of the treating physician and SIRS criteria.
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