Virtual Single-energy Imaging and De-metallic Artifact Technology in Reducing Spinal Metallic Artifacts

Completed

• Conditions: Spinal Disease
• Interventions: Diagnostic Test: Virtual single energy combined with MAR reconstruction group

• Registration Number: NCT04955483
• Lead Sponsor: Peking University Third Hospital

Brief Summary

1. Compare the effect of virtual single energy imaging and virtual single energy combined with MAR technology to remove metal artifacts in the spine. 2. Discuss the most suitable KeV of virtual single energy imaging combined with MAR technology to remove metal artifacts.

Detailed Description

The virtual single-energy imaging of energy spectrum CT combined with the metal artifact reduction technology MARS Multi Artifact Reduction System\] can effectively reduce the interference of metal artifacts. This is because MAR technology corrects the image through an iterative algorithm, improves the spatial resolution, and restores the details of the adjacent tissue of the metal object. Virtual single-energy imaging technology can effectively reduce hardening artifacts. The two are used in combination to achieve the purpose of reducing metal artifacts. There have been articles about virtual single energy combined with MAR technology to reduce metal artifacts. However, the current researches mostly focus on the comparison of virtual single energy combined with MAR technology and conventional CT examination and virtual single energy imaging. There are few evaluations on the severity of metal artifacts after spinal surgery. According to different surgical methods, metal The difference in the number of implants will result in different artifact reduction effects. Secondly, the current research on the suitable KeV of virtual single energy combined with MAR technology to reduce metal artifacts is less discussed and reported.

Study Timeline

• Status Verified: 2018-12
• Study Start: 2018-12-01
• Primary Completion: 2018-12-03
• Study Completion: 2019-02-01
• Study First Submitted: 2021-06-29
• Study First Submitted QC: 2021-07-01
• Last Update Submitted: 2021-07-01
• Study First Posted: 2021-07-08
• Last Update Posted: 2021-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 43

Inclusion Criteria

• Patients undergoing surgery due to lumbar disc herniation or prolapse
• Patients undergoing surgical correction due to vertebral deformities.

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Exclusion Criteria

• The scan image quality caused by the patient's movement and other factors is too poor to meet the diagnostic requirements.
• Patients with only spinous processes and intervertebral spaces undergoing metal fixation after spine surgery
• Patients after spinal cord tumor surgery.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Virtual single energy (70-140Kev, interval 10Kev) combined with MAR reconstruction group	Virtual single energy combined with MAR reconstruction group	Rebuild a virtual single energy map (70-140Kev, interval 10Kev) combined with MAR reconstruction group

Primary Outcome Measures

Name	Time	Method
Artifact Index	2019.2.1-2019.2.15	Select the largest level of artifacts in the image, place a region of interest (ROI) with an area of 100-150mm2 in the soft tissue around the metal and spinal canal for CT value and standard deviation (SD) measurement, avoid the boundary area, and measure the ROI area Artifact Index ASelect the largest level of artifacts in the image, place a region of interest (ROI) with an area of 100-150mm2 in the soft tissue around the metal and spinal canal for CT value and standard deviation (SD) measurement, avoid the boundary area, and measure the ROI area Artifact Index AI

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China