Study on evaluation of therapeutic efficacy and search for a therapeutic biomarker in dry eye with rebamipide eye drop treatment. - Evaluation of therapeutic efficacy and therapeutic biomarker in dry eye with rebamipide eye drop treatment.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine.0 sites55 target enrollmentDecember 1, 2012

ConditionsDry eye

Overview

Phase: N/A
Intervention: Not specified
Conditions: Dry eye
Sponsor: Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine.
Enrollment: 55
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

December 1, 2012

End Date

April 30, 2015

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Investigators

Sponsor

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine.

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•a) Patients with dry eye. 1\) Patients with anterior segment disease (including blepharitis, lagophthalmos, blepharospasm, iritis and conjunctivochalasis) other than dry eye (History is excluded). 2\) Patients who cannot discontinue eye drops (include all eye drops such as prescribed drug and OTC medicine) except for the study drug or the control drug from the study initiation until the end of study treatment or who expect to use those drugs. 3\) Patients with punctal plug or patients whose punctal plug fell off within three months prior to the study drug initiation examination. Patients with a history ofsurgical punctual occlusion are also excluded. 4\) Patients with a history of surgery of the ocular surface within 12 months, or patients with a history of intraocular surgery within three months prior to the study drug initiation examination. 5\) Patients who have difficulty in sampling. 6\) Patients that a study supervisor or a study partaker judged participation in this study to be inappropriate. b) Non\-dry eye patients 1\) Patients with anterior segment disease. 2\) Patients who used eye drops or the contact lens within two weeks prior to study initiation. 3\) Patients with a history of surgery of the ocular surface within 12 months or patients with a history of intraocular surgery within three months prior to the study drug initiation examination. 4\) Patients who have difficulty in sampling. 5\) Patients that a study supervisor or a study partaker judged participation in this study to be inappropriate.