Effects of Moderate Aerobic Exercise and Inspiratory Muscle Training on selected Clinical and Haematological Parameters Among Adults with Sickle Cell Disease
Phase 3
- Conditions
- Haematological Disorders
- Registration Number
- PACTR202001495245937
- Lead Sponsor
- Bayero University Kano
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
1.Diagnosis of Sickle Cell Disease type HbSS following electrophoresis test
2.Restricted pattern of spirometry.
3.Adults, aged 18 years and above who are able to perform pulmonary function test.
4.Patients who can understand instructions on how to carry out the procedure involved in this study
5.A non-smoker Sickle Cell Anaemia (SCA) patient.
6.Steady state patients that have not had crises for at least 1 month and no blood transfusion.
7.Individuals with no prior asthma history.
Exclusion Criteria
1.Chronic lung diseases unrelated to sickle cell disease, such as COPD, asthma
2.Heart disease and pulmonary hypertension
3.Individuals with avascular necrosis
4.Individuals on hydroxyuria drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ung Function Test
- Secondary Outcome Measures
Name Time Method Respiratory muscle strength, Functional capacity, Quality of life, respiratory symptoms, Full blood count and Lactate Dehydrogenase