Comparison of bone forming ability of reamer irrigator-aspirator (ria) apparatus with iliac crest bone graft (icbg)

Not Applicable

Conditions: Health Condition 1: S723- Fracture of shaft of femur

Registration Number: CTRI/2023/01/049187

Lead Sponsor: All India Institute of Medical Sciences, New Delhi

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Diagnosis of isolated femoral shaft fractures amenable to fixation with an antegrade IM nail

2. Patients with pelviacetabular fractures other fractures or bone grafting procedures necessitating operative intervention

3. Patients giving informed, written consent to be a part of the study

Exclusion Criteria

1. Femoral shaft fractures not amenable to antegrade intramedullary nailing

2. Open fractures

3. Pathological fracture

4. Patients having any of these comorbid conditions: Intracranial events (stroke, bleeding, infection), Fluid or electrolyte disturbances (including dehydration, hyponatremia, Hypernatremia), Acute cardiac events:

myocardial infarction, congestive heart failure

exacerbation, arrhythmia, Acute pulmonary events: asthma or chronic obstructive pulmonary disease exacerbation, pulmonary embolism, hypoxemia, hypercarbia, on anti coagulants or antiplatelet drugs.

- history of leukaemia, cancer with bone metastases, renal

failure, patients on dialysis or receiving

immunosuppressive medication, and those with suspected

local or systemic infection. â??

5. Patients not giving consent

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To estimate the release of osteogenic growth factors in the graft aspirate obtained using the reamer irrigator aspirator (RIA) technique for intramedullary nailing of femoral shaft fractures and compare it with that of iliac crest bone graft.Timepoint: From sample taken during surgery (Baseline). No other follow up assesments

Secondary Outcome Measures