Cohort Study: Perceptual Urge Sensation

Completed

• Conditions: Osteoporosis; Urinary Bladder, Overactive
• Interventions: Other: Micturition diary; Other: Hospital Anxiety and Depression scale; Other: EuroQol-5D; Other: Self-consciousness questionnaire

• Registration Number: NCT00971646
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

Over the past few years it has become clear that our understanding of bladder physiology is inadequate to explain urge incontinence. This has forced us to re-evaluate what we know and do not know about bladder function and dysfunction. This has led to the identification and study of novel systems within the bladder that may contribute to abnormal sensations.

The investigators now suspect that the organic changes occurring in the bladder are not the whole story. For one group of patients with pathological urge there is growing evidence suggesting that there may be a strong psychological component. The idea now being put forward is that normal afferent peripheral information is perceived as abnormal and excessive, resulting in an increased desire to go to the bathroom: 'perceptual urge'. It is important to identify this group of patients since it will direct their treatment towards more cognitive approaches. Also, if such a psychological aetiology can be eliminated it would lead to a more focused and effective management of peripheral pathology with surgery or pharmacology.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-09-03
• Study First Submitted QC: 2009-09-03
• Study First Posted: 2009-09-04
• Study Start: 2010-06
• Primary Completion: 2017-03-01
• Study Completion: 2017-03-01
• Status Verified: 2018-09
• Last Update Submitted: 2018-09-04
• Last Update Posted: 2018-09-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
OAB	Micturition diary	Patients with overactive bladder syndrome
OAB	Hospital Anxiety and Depression scale	Patients with overactive bladder syndrome
OAB	EuroQol-5D	Patients with overactive bladder syndrome
Osteoporosis	EuroQol-5D	Patients with osteoporosis
Osteoporosis	Self-consciousness questionnaire	Patients with osteoporosis
OAB	Self-consciousness questionnaire	Patients with overactive bladder syndrome
Osteoporosis	Hospital Anxiety and Depression scale	Patients with osteoporosis
Osteoporosis	Micturition diary	Patients with osteoporosis

Primary Outcome Measures

Name	Time	Method
Defining differences in self-consciousness and HADS scores in patients with OAB	1 year

Secondary Outcome Measures

Name	Time	Method
Defining differences in quality of life between the two cohorts	1 year
Defining differences between self-consciousness and HADS scores between the two cohorts	1 year

Trial Locations

Locations (1)

Maastricht University Medical Centre; 🇳🇱 Maastricht, Limburg, Netherlands