Evaluation of Clinical and Genetic Modifiers of Long-term Survival in Heart Failure
- Conditions
- Heart Failure
- Interventions
- Other: No intervention
- Registration Number
- NCT03461107
- Lead Sponsor
- Tongji Hospital
- Brief Summary
The purpose of this study is to evaluate the beta-adrenergic receptor gene polymorphisms in the long-term effects of beta-blockade in patients with chronic heart failure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 2500
Inclusion Criteria
- 18 years of age or older;
- Patients are required to have chronic heart failure (NYHA II-IV) with a left ventricular ejection fraction lower than 40%;
- Patients are voluntary and signed informed consent.
Exclusion Criteria
- Pregnant women or plan to;
- Participate in any drug clinical trials within 3 months;
- Serious neurological disease (Alzheimer's disease, Parkinson syndrome, progressive lower limbs or deaf patients);
- Previous history of cancer or tumor, or pathological examination confirmed precancerous lesions;
- Patients refused to comply with the requirements of this study to complete the research work;
- According to the researchers, patients can not complete the study or not to comply with the requirements of this study (because of the reasons for the management or other reasons).
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description patients with heart failure No intervention -
- Primary Outcome Measures
Name Time Method Cardiovascular death up to 24 months Heart transplantation up to 24 months
- Secondary Outcome Measures
Name Time Method Readmission because of cardiovascular diseases up to 24 months All cause death up to 24 months Heart failure recuring up to 24 months
Trial Locations
- Locations (1)
Tongji Hospital
🇨🇳Wuhan, Hubei, China