Prediction of Lymphatic Metastasis in Esophageal Cancer by CT Radiomics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 133
- 试验地点
- 1
- 主要终点
- pathological local lymph node status
研究概览
简要总结
This study proposes to establish a CT radiomics-based prediction model for identifying metastasis lymph nodes in esophageal cancer.
详细描述
This study proposes to establish an image feature extraction and selection method for identifying lymph node metastasis of esophageal cancer.The study will consider the relationship between the main lesion and the suspected lymph node, extract association characteristics in order to improve the sensitivity and specificity of the CT radiomics-based prediction model for identifying metastasis lymph nodes. The study includes the construction of CT radiomics-based prediction model and the validation of the prediction model.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pathologically proven esophageal cancer
- •scheduled to preoperative enhanced chest CT and undergo surgery
- •sign the patient informed consent
排除标准
- •failed to receive preoperative enhanced chest CT or undergo surgery
- •inavailable pathological results for local lymph node status
- •inquality of CT images for feature extraction
- •patient quit
结局指标
主要结局
pathological local lymph node status
时间窗: Pathologic evaluation will be performed for each patient within 1 week after surgery
pathological lymph node status is defined as lymph node metastasis exist or not
次要结局
未报告次要终点
研究者
Sun Ying-Shi
Chairman of Dept.Radiology of Beijing Cancer Hospital
Peking University Cancer Hospital & Institute