Carpal Tunnel Syndrome and Amyloidosis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Number of participants with amyloid deposits in patients undergoing carpal tunnel surgery
研究概览
简要总结
Carpal tunnel syndrome has been suggested to be an early sign of amyloidosi. The investigators will evaluate tissue samples obtained from patients undergoing carpal tunnel release surgery for amyloid.
详细描述
Carpal tunnel syndrome (CTS) can be caused by the deposition and accumulation of misfolded proteins called amyloid and is often an early manifestation of systemic amyloidosis.
Patients with cardiac amyloidosis often have carpal tunnel syndrome that precedes cardiac manifestations by several years, and many patients will have undergone surgery for idiopathic carpal tunnel syndrome since the protein also deposits in the transversal carpal ligament of the hand.
The investigators sought to identify the prevalence and type of amyloid deposits in patients undergoing carpal tunnel surgery and evaluate for cardiac involvement
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing carpal tunnel syndrome surgery
排除标准
- 未提供
结局指标
主要结局
Number of participants with amyloid deposits in patients undergoing carpal tunnel surgery
时间窗: 2 years
Prevalence of amyloid deposits in biopsy in patients undergoing carpal tunnel syndrome surgery
次要结局
- Number of participants with cardiac involvement in echocardiogram(2 years)
研究者
Maria del Carmen Navarro-Saez
Principal Investigator
Corporacion Parc Tauli