NCT05409833招募中不适用
Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese Population (CarPoS Study)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Frequency of transthyretin amyloidosis in synovial in patients with ≥60 years old
研究概览
简要总结
Systemic transthyretin amyloidosis is an aging-related disorder. It is usually associated with cardiac disease but also extends to other organs. Recent studies found that idiopathic carpal tunnel syndrome patients may have amyloid deposition in tenosynovial tissue. The main aims of this project are the characterization of the association between idiopathic carpal tunnel syndrome and transthyretin amyloidosis and its evaluation as a predictive factor of cardiac amyloidosis
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •. Patients aged ≥ 60 years old with symptomatic idiopathic carpal tunnel syndrome or other hand surgery indications.
排除标准
- •. Diabetes mellitus, hypothyroidism, hemodialysis, rheumatoid arthritis, and other inflammatory arthropathies, multiple myeloma, gout, chondrocalcinosis, Colles fracture, space-occupying lesions, and infectious synovitis.
结局指标
主要结局
Frequency of transthyretin amyloidosis in synovial in patients with ≥60 years old
时间窗: 24 months
Number of patients with transthyretin amyloidosis in synovial in relation to total number of patients submitted to hand surgery
次要结局
- Association between idiopathic carpal tunnel syndrome with cardiac transthyretin amyloidosis(24 months)
- Association between synovial transthyretin amyloidosis with carpal tunnel syndrome(24 months)
研究者
研究点 (2)
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