Results of perioperative management and surgical treatment of primary colon carcinoma (KK) at a university surgical center over a 10-year period with a comparison of the multicentre observational study Quality control colon carcinoma (primary tumor) - elective surgery (AN Institute for Quality assurance in operative medicine GmbH at Otto von Guericke University Magdeburg)
- Conditions
- C18.9Colon, unspecified
- Registration Number
- DRKS00017030
- Lead Sponsor
- niversitätsklinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 614
Patients with care in the period from 01.10.2002 to 30.09.2012 under elective, urgent or emergency indication with pre-operative or postoperatively histologically confirmed primary colon carcinoma and primary surgical care. Tumor localization at the colon between the ileocecal (Bauhinian) flap to 16 cm orally of the anocutaneous line (measured with a rigid rectoscope).
- Preoperative surgical care of primary colon carcinoma in an external care facility
- Surgical treatment of benign tumors and potential precancerous lesions that are not classified by histological classification as malignant colon tumors
- Single operative care of metastases or synchronous metastases and local recurrences of primary external patients
- Patients with a colon carcinoma primarily without definite preoperative height indication of the tumor localization in the rectosigmoid transition with intraoperatively proven rectal localization and resulting, more rectal carcinoma-specific surgical procedures
- Colon carcinoma patients who did not receive oncosurgical care
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The data collected cover patients who were in treatment from October 2002 to September 2012.<br><br>- Description of the treatment aspects (Among other things, determination of the surgical rate, resection rates, complication rates incl. Study period)<br>- Influence of:<br>* Patient (including age, gender, obesity, comorbidity profile [ASA score]),<br>* Tumor / findings (including tumor location, depth infiltration, UICC stage, histological detected nodal / lymph vessel / venous invasion, metastasis),<br>* Therapy-associated characteristics (urgency of operation (elective / emergency, surgical Indication (curative, palliative, antibiotics, surgical method)<br>and their influence on postoperative morbidity (general and special complications, especially anastomotic leakage, hospital allotment, spleen injury, wound healing disorders, peritonitis, hemorrhage).<br>- Influence of the described aspects on overall survival (OS), disease-free survival (DFS) and local recurrence rate (LRR).
- Secondary Outcome Measures
Name Time Method Comparison of early postoperative outcome, OS and DFS and LRR - representative of the long-term oncosurgical outcome - in defined groups of the patient cohort to the multicentric study Quality Assurance Colon Carcinoma (Primary Tumor) -Electual Surgery (AN Institute for Quality Assurance in the operative Medizin GmbH at the Otto-von-Guericke University Magdeburg) as well as evaluation in the subdivided 10-year (investigation) period with regard to significant changes and trends.<br>