Comparing feeding jejunostomy with nasojejunal tube placement in patients undergoing oesophagectomy: A pilot study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Rate of complications in both groups of patients: those undergoing nasojejunal tube feeding versus surgical feeding jejunostomy
研究概览
简要总结
Early enteral nutrition is one of the key goals and is preferred over parenteral nutrition following oesophagectomy. It improves postoperative outcomes by maintaining gut mucosal integrity and improving immunological functioning. Feeding jejunostomy as a means of enteral access is being used routinely at many centres, but is associated with complications. Nasojejunal tube feeding is an alternative access route to establish enteral nutrition. There has been only one randomized control trial in patients with oesophageal cancer, in a western population, comparing feeding jejunostomy with nasojejunal tube feeding. There exists a paucity of studies in the Asian population, evaluating the safety and efficacy of nasojejunal tube feeding. We aim to compare feeding jejunostomy with nasojejunal tube feeding in terms of efficacy and complications in Indian patients undergoing gastric/colonic pull-up and cervical oesophageal anastomosis for carcinoma oesophagus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, fixed
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients undergoing oesophagectomy for carcinoma oesophagus.
排除标准
- •1.Those who refuse consent to participate in the study 2.Patients with any nasopharyngeal or oropharyngeal obstruction preventing insertion of nasojejunal tube.
结局指标
主要结局
Rate of complications in both groups of patients: those undergoing nasojejunal tube feeding versus surgical feeding jejunostomy
时间窗: Post operatively, till the time of removal of feeding jejunostomy tube at 6 weeks.
次要结局
- 1.To compare catheter efficacy of nasojejunal tube feeding with surgical feeding jejunostomy in terms of:(Time to full establishment of oral intake)
- 2.To compare the discomfort associated with surgical feeding jejunostomy versus nasojejunal tube using the visual analogue scale.(From post operative day 2 till the time of removal of nasojejunal tube)
- 3.To compare the quality of life with a surgical feeding jejunostomy with nasojejunal feeding tube using the WHOQOL-BREF questionnaire(Self reported at the time of discharge and at 6 weeks follow up.)