Examining associations between proteins in the blood and cognitive function among patients undergoing cardiac and non-cardiac surgery (BRAIN-S)

Not Applicable

Recruiting

• Conditions: Delirium; Postoperative Cognitive Dysfunction; Anaesthesiology - Anaesthetics; Neurological - Dementias; Surgery - Other surgery; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12620000254998
• Lead Sponsor: St Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-02-26
• Last Update Posted: 13 June 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

1. Greater than or equal to 65 years of age
2. Scheduled for elective cardiac or non-cardiac surgery (excluding valvular surgery, to avoid confounding factors of solid and air emboli)
3. Elective non-cardiac surgery procedures anticipated to last greater than one hour
4. Have no contraindication to neuropsychological testing (e.g. language, visual or hearing impairment)
5. Reside in an accessible proximity to the hospital for neuropsychological testing

Exclusion Criteria

1. Pre-existing neurological or clinically evident neurovascular disease (e.g. stroke)
2. Dementia of any aetiology
3. Undergone general anaesthetic in past 6 months
4. Associated medical problems that may lead to significant complications and loss to follow-up

Study & Design

• Study Type: Observational
• Study Design: Not specified