Biomarker Use in Evidence of Neuronal Damage in Response to Anaesthesia and Surgery (The BOUNDARY Study)

Not Applicable

Recruiting

• Conditions: Delirium; Postoperative Cognitive Dysfunction; Anaesthesiology - Anaesthetics; Neurological - Dementias; Surgery - Other surgery

• Registration Number: ACTRN12620000101987
• Lead Sponsor: St Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-02-05
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 118

Inclusion Criteria

1. 65 years of age
2. Scheduled for elective non-cardiac surgery
3. Undergoing a procedure equally suited to intravenous (TIVA) or volatile anaesthetic management
4. Have no contraindication to neuropsychological testing (e.g. language, visual or hearing impairment)
5. Reside in an accessible proximity to the hospital for neuropsychological testing

Exclusion Criteria

1. Pre-existing neurological or clinically evident neurovascular disease (e.g. stroke)
2. Dementia of any aetiology
3. Received a general anaesthetic in previous 6 months
4. Associated medical problems that may lead to significant complications and loss to follow-up

Study & Design

• Study Type: Interventional
• Study Design: Not specified