Comparative efficacy of intravenous dexmedetomidine and intravenous dexamethasone on the incidence of postoperative nausea and vomiting in patients undergoing gynaecological laparoscopic surgery
Overview
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Vardhman Mahavir Medical College and Safdarjung Hospital
- Enrollment
- 84
- Locations
- 1
- Primary Endpoint
- To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
Overview
Brief Summary
This study is undertaken to compare the efficacy of dexmedetomidine and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing gynaecological laparoscopic surgery.primarily Postoperative nausea and vomiting score will be recorded and secondarily intraoperative hemodynamic parameters , sedation score and postoperative pain using visual analog scale will be assessed.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •Patients of age 18-65 years with American society of Anesthesiologist I and II undergoing gynaecological laparoscopic surgery.
Exclusion Criteria
- •1.patients with a known history of Gastric esophageal Reflux Disease 2.Allergic to study drugs 3.Body mass index ≥30kg/m2.
Outcomes
Primary Outcomes
To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
Time Frame: To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
Secondary Outcomes
- To compare the postoperative nausea and vomiting score using visual analog scale(0 hr, 4 hrs,12hrs)
- Intraoperative hemodynamic parameter(Intraoperatively every 5 mins vital parameters will be assessed)
- Sedation score(Postoperatively using Ramsay sedation score)
- Postoperative pain(Postoperatively using visual analog scale)
Investigators
Gnanavel R
Vardhman Mahavir Medical College and Safdarjung Hospital