Comparative efficacy of intravenous dexmedetomidine and intravenous dexamethasone on the incidence of postoperative nausea and vomiting in patients undergoing gynaecological laparoscopic surgery
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
研究概览
简要总结
This study is undertaken to compare the efficacy of dexmedetomidine and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing gynaecological laparoscopic surgery.primarily Postoperative nausea and vomiting score will be recorded and secondarily intraoperative hemodynamic parameters , sedation score and postoperative pain using visual analog scale will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •Patients of age 18-65 years with American society of Anesthesiologist I and II undergoing gynaecological laparoscopic surgery.
排除标准
- •1.patients with a known history of Gastric esophageal Reflux Disease 2.Allergic to study drugs 3.Body mass index ≥30kg/m2.
结局指标
主要结局
To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
时间窗: To compare the postoperative nausea and vomiting score using visual analog scale at 8 hrs after administration of dexmedetomidine and dexamethasone in patients undergoing gynaecological laparoscopic surgeries
次要结局
- To compare the postoperative nausea and vomiting score using visual analog scale(0 hr, 4 hrs,12hrs)
- Intraoperative hemodynamic parameter(Intraoperatively every 5 mins vital parameters will be assessed)
- Sedation score(Postoperatively using Ramsay sedation score)
- Postoperative pain(Postoperatively using visual analog scale)
研究者
Gnanavel R
Vardhman Mahavir Medical College and Safdarjung Hospital