A study comparing the effectiveness of 20% mannitol versus 3% saline to see if there is any difference in outcome of patients who are undergoing surgery for brain tumor.
Not Applicable
Completed
- Conditions
- Health Condition 1: C719- Malignant neoplasm of brain, unspecified
- Registration Number
- CTRI/2019/09/021218
- Lead Sponsor
- All India Institute of Medical Sciences Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 140
Inclusion Criteria
•18- 60 years
•Both gender
•ASA I and ASA II
•All supratentorial tumors both intraaxial and extra-axial measuring less than 10 cm in any dimension posted for craniotomy in elective neurosurgery OT in AIIMS Bhubaneswar.
Exclusion Criteria
1 Emergency cases
2 Receiving Mannitol or HTS in previous 24 hours
3 GCS <10
4 Raised serum creatinine > 1.2 mg/dl
5 Preoperative hyponatremia (Na <130)
6 Preoperative hypernatremia (Na >145)
7 Deep location of tumour.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method