Efficacy of TAP Block in Cesarean Section Patients
Phase 3
Completed
- Conditions
- Pain Control
- Interventions
- Procedure: TAP block using Bupivacaine 0.25%Procedure: TAP block using Bupivacaine 0.5%Procedure: TAP block using Normal Saline
- Registration Number
- NCT03493828
- Lead Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
- Brief Summary
TAP Block done with 2 different concentrations of bupivacaine and placebo
- Detailed Description
TAP Block was done using 2 different concentrations of bupivacaine (0.5% and 0.25%) and placebo and the post operative sedation was measured in each arm and compared together.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
- Healthy pregnant women
Exclusion Criteria
- Allergy to local anesthetics
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description TAP using Bupivacaine 0.25% TAP block using Bupivacaine 0.25% Following completion of the Cesarean delivery, the abdomen was aseptically prepped with ChloraPrep®. A Sonosite ultrasound machine (S-nerve) with a 14-8 MHz linear probe was used to visualize the lateral abdominal wall muscles and transversus abdominis plane. A 2 or 4 inch stimuplex (Braun) needle was advanced under ultrasound guidance to the transversus abdominis plane. After negative aspiration, 15 ml of Bupivacaine 0.25% was incrementally injected on each side. The spread of solution within the transversus abdominis plane was visualized with the ultrasound. TAP using Bupivacaine 0.5% TAP block using Bupivacaine 0.5% Following completion of the Cesarean delivery, the abdomen was aseptically prepped with ChloraPrep®. A Sonosite ultrasound machine (S-nerve) with a 14-8 MHz linear probe was used to visualize the lateral abdominal wall muscles and transversus abdominis plane. A 2 or 4 inch stimuplex (Braun) needle was advanced under ultrasound guidance to the transversus abdominis plane. After negative aspiration, 15 ml of Bupivacaine 0.5% was incrementally injected on each side. The spread of solution within the transversus abdominis plane was visualized with the ultrasound. Placebo TAP block using Normal Saline Following completion of the Cesarean delivery, the abdomen was aseptically prepped with ChloraPrep®. A Sonosite ultrasound machine (S-nerve) with a 14-8 MHz linear probe was used to visualize the lateral abdominal wall muscles and transversus abdominis plane. A 2 or 4 inch stimuplex (Braun) needle was advanced under ultrasound guidance to the transversus abdominis plane. After negative aspiration, 15 ml of normal saline was incrementally injected on each side. The spread of solution within the transversus abdominis plane was visualized with the ultrasound.
- Primary Outcome Measures
Name Time Method Effect of Transversus Abdominis Plane (TAP) Block Using Either 0.5% or 0.25% Bupivacaine on Analgesia for Cesarean Section Patients When Compared to Placebo. 0-24 hours The total the number of Patient Controlled Analgesia (PCA) boluses used by the patients postoperatively within 24 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
New York Methodist Hospital
🇺🇸Brooklyn, New York, United States