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Clinical Trials/NCT01915810
NCT01915810
Active, not recruiting
Not Applicable

Using Physical Activity to Facilitate Smoking Cessation Among African American Adults

M.D. Anderson Cancer Center1 site in 1 country45 target enrollmentJanuary 29, 2014

Overview

Phase
Not Applicable
Intervention
Exercise Intervention
Conditions
Current Smoker
Sponsor
M.D. Anderson Cancer Center
Enrollment
45
Locations
1
Primary Endpoint
Recruitment feasibility, defined as >= 75% of eligible/screened participants choose to enroll in the study
Status
Active, not recruiting
Last Updated
3 months ago

Overview

Brief Summary

This randomized pilot clinical trial studies the use of physical activity in promoting the discontinuation of the habit of smoking (smoking cessation) in African Americans. Participating in physical activity during an actual smoking quit attempt may work better in helping African Americans stop smoking.

Detailed Description

PRIMARY OBJECTIVES: I. Evaluate the feasibility of a Smoking Cessation with Physical Activity (SCwPA) intervention among an African American (AA) church-based sample of adult current smokers. II. Conduct post-intervention focus groups to obtain feedback from pilot participants regarding the acceptability of the SCwPA project design and procedures. III. Examine how physical activity (PA) and the timing of PA initiation affects the mechanisms underlying cessation among an AA church-based sample of adult daily smokers who are attempting to quit. OUTLINE: Participants are randomized to 1 of 3 arms. ARM I (PRE-QUIT PHYSICAL ACTIVITY): Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks. ARM II (QUIT DAY PHYSICAL ACTIVITY): Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks. ARM III (NO PHYSICAL ACTIVITY): Participants quit smoking on an assigned date and receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks.

Registry
clinicaltrials.gov
Start Date
January 29, 2014
End Date
January 31, 2027
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Self-reported African-American race
  • Current daily smoker (has smoked \>= 100 cigarettes in lifetime per self-report, smoked \>= 5 cigarettes per day for the last 6 months per self-report)
  • Self-reports motivation to quit smoking within the next 2 weeks
  • Reports willingness to engage in a physical activity-based smoking cessation intervention
  • Has a home address and a functioning home and/or cell phone number
  • Able to engage in moderate intensity physical activity as determined by the Physical Activity Readiness Questionnaire (PAR-Q) or by physicians clearance (letter from physician or nurse practitioner) if currently taking medication for blood pressure or diabetes
  • Willingness to wear the nicotine patches provided in the study as recommended
  • Have an expired carbon monoxide (CO) level \> 8 parts per million (ppm) suggestive of current smoking
  • Blood pressure =\< 140/90mm or by physicians clearance (letter from physician or nurse practitioner) if blood pressure reading \> 140/90mm Hg

Exclusion Criteria

  • Contraindication for nicotine patch use
  • Regular use of tobacco products other than cigarettes in the last 30 days (including black \& milds)
  • Current or planned future use of any nicotine replacement or pharmacological product for smoking cessation other than the study patches
  • Pregnancy or lactation
  • Another household member enrolled in the study
  • A schedule not accommodating to the study procedures, or unwillingness to adhere to the procedures

Arms & Interventions

Arm I (pre-quit physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks.

Intervention: Exercise Intervention

Arm I (pre-quit physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks.

Intervention: Laboratory Biomarker Analysis

Arm I (pre-quit physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks.

Intervention: Nicotine Patch

Arm I (pre-quit physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks.

Intervention: Questionnaire Administration

Arm I (pre-quit physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning 2 weeks before the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise activity per week for 5 weeks.

Intervention: Tobacco Cessation Counseling

Arm II (quit day physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks.

Intervention: Exercise Intervention

Arm II (quit day physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks.

Intervention: Laboratory Biomarker Analysis

Arm II (quit day physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks.

Intervention: Nicotine Patch

Arm II (quit day physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks.

Intervention: Questionnaire Administration

Arm II (quit day physical activity)

Participants receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks. Beginning on the assigned quit date, participants receive a Walking Program guide and engage in the SCwPA comprising brisk, self-paced walking with a goal of 150 minutes of exercise per week for 5 weeks.

Intervention: Tobacco Cessation Counseling

Arm III (no physical activity)

Participants quit smoking on an assigned date and receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks.

Intervention: Laboratory Biomarker Analysis

Arm III (no physical activity)

Participants quit smoking on an assigned date and receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks.

Intervention: Nicotine Patch

Arm III (no physical activity)

Participants quit smoking on an assigned date and receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks.

Intervention: Questionnaire Administration

Arm III (no physical activity)

Participants quit smoking on an assigned date and receive telephone-based cessation counseling over 15-20 minutes 1-2 weeks before assigned quit date and nicotine patch for 6 weeks.

Intervention: Tobacco Cessation Counseling

Outcomes

Primary Outcomes

Recruitment feasibility, defined as >= 75% of eligible/screened participants choose to enroll in the study

Time Frame: Up to 8 weeks

Retention feasibility, defined as an overall retention rate of 80% and if each enrolled participant completes >= 66.7% of study visits (>= 6 of 9 study visits)

Time Frame: Up to 8 weeks

Post intervention focus group analysis

Time Frame: Up to 8 weeks

Each focus group will use a semi-structured interview guide for consistency, which will consist of approximately 15 open-ended questions. If results do not suggest intervention feasibility, post-intervention focus groups will help to identify why feasibility was not achieved. Focus group transcripts will be imported into a qualitative data analysis software program, such as NVivo, to facilitate data retrieval and analysis and to organize data by themes based on phrases, patterns, relationships, and commonalties or disparities.

Secondary Outcomes

  • Mechanisms underlying smoking cessation (e.g., stress, positive and negative affect, depression, smoking urges, self-efficacy, motivation, PA enjoyment, and heart rate variability)(Up to 8 weeks)

Study Sites (1)

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