EUCTR2019-004541-33-SE
Active, not recruiting
Phase 1
A clinical study to examine cellular and humoral immunity against measles and chickenpox in children and adolescents 0-18 years in childhood cancer. - immvzmpr1
ConditionsThis study will be conducted as a longitudinal study. Former studies have shown that immunity is affected after treatment against childhood cancer. We want to investigate humoral and cell-mediated immunity specifically targeted for varicella and measles, during and after treatment for childhood cancer. We also want to investigate vaccin response for varicella and measles.Therapeutic area: Diseases [C] - Cancer [C04]
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- This study will be conducted as a longitudinal study. Former studies have shown that immunity is affected after treatment against childhood cancer. We want to investigate humoral and cell-mediated immunity specifically targeted for varicella and measles, during and after treatment for childhood cancer. We also want to investigate vaccin response for varicella and measles.
- Sponsor
- Västra Götalandsregionen
- Enrollment
- 160
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Children and young people (0\-18\.0 years) who start cancer treatment at the childhood cancer center in Gothenburg.
- •Known vaccination status for measles and chickenpox before start of cancer treatment.
- •Oral and written information for the study and signed consent form.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range: 160
- •F.1\.2 Adults (18\-64 years) no
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •Known pre\-existing primary immunodeficiency.
- •Patients planned for relapse therapy or will undergo allogeneic stem cell transplantation (SCT).
- •Known contraindication to any of the suggested vaccines.
Outcomes
Primary Outcomes
Not specified
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