Analgesic Effect of Using Dexmedetomidine as an Additive for (Ipack)Block in Knee Surgeries in Adult Patient; A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Visual Analog Scale at rest score during first postoperative 48 hours
研究概览
简要总结
Dexmedetomidine used as an Additive for Ipack Block in Knee Surgery
详细描述
Many types of analgesia used but multimodal analgesia showed best results The interspace between the popliteal artery and capsule of the posterior knee (IPACK) block aims to blockade of sciatic nerve terminal branches for analgesia without motor affection
. (IPACK) block is a motor power sparing procedure that involves injecting local anesthetic into the space between the popliteal artery and the posterior capsule of the knee in order to treat posterior knee pain
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-60 years
- •ASA I, II .patients undergoing knee surgeries.
排除标准
- •patient Refusal
- •bleeding disorders
- •skin lesion
- •infection
- •known allergy
- •contradictions of spinal anesthesia
研究组 & 干预措施
Bupivacaine
IPACK block with 20ml bupivacaine 0.25% alone.
.
干预措施: Bupivacaine (Drug)
Dexmedetomidine
IPACK block with 20 ml of bupivacaine 0.25% with dexmedetomidine 100 μg as adjuvant.
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Visual Analog Scale at rest score during first postoperative 48 hours
时间窗: 48 postoperative hours
Visual Analog Scale at rest during first postoperative 48 hours a line 10centimeters long from zero to10 where 10 is the worst pain ever
次要结局
- Incidence of adverse effects(2 hours inPACU)
- Visual Analog Scale at rest and during movement at 30 minuts, 2, 8, 16, 24, 36, and 48 hours(48 postoperative hours)
- Duration of the block(48 hours)
- Heart Rate(48 hours)
- Mean Arterial Pressure(48 hours)
- Block performance time in minutes(preoperative)
研究者
Dalia Ismail
Associate Professor of Anesthesia, Surgical ICU and pain management at Faculty of medicine Cairo University
Cairo University