The impact of Early versus Late Complete revascularization On Remodeling of the Left Ventricle in ST-elevation Myocardial Infarction with multivessel disease after primary PCI.

Withdrawn

• Conditions: hartinfarct, herstel na behandeling van linker kamer; remodelling of the left ventricle; treatment of multivessel disease; 10011082; 10003216

• Registration Number: NL-OMON41253
• Lead Sponsor: HagaZiekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

primary PCI, STEMI, multivessel disease, older than 18 years, hemodynamic stable

Exclusion Criteria

cardiogenic shock, resucitation, intra-aortic balloon pump, mechanical ventilation, prior infarction or CABG, life expectancy less than 2 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary aim of our study is to assess the association of timing of CR and<br /><br>left ventricular remodelling (increase in end diastolic volume [EDV]>20%) or an<br /><br>increase of at least 5% in left ventricular function after primary PCI in STEMI<br /><br>patients with multi-vessel disease. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary objective of our study is to assess the correlation of plasma<br /><br>serum BNP level within the first 24-96 hours of STEMI and the development of<br /><br>subsequent left ventricular dilatation according to CR-group at 3, 6 and 12<br /><br>months of follow-up on imaging (serial MRI and/or echocardiography) and<br /><br>mortality (all cause and cardiac).</p><br>