Complete revascularization versus culprit lesion only PCI in NSTEMI

Not Applicable

Recruiting

• Conditions: non-ST-elevation myocardial infarction (NSTEMI)Multivessel coronary artery disease; I21.4; I25.12; I25.13; Acute subendocardial myocardial infarction

• Registration Number: DRKS00031653
• Lead Sponsor: eipzig Heart Science gGmbH

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 3390

Inclusion Criteria

• NSTEMI as suggested by high-sensitivity troponin algorithms
• Multivessel coronary artery disease
• Identifiable culprit lesion
• Informed consent

Exclusion Criteria

• Cardiogenic shock
• Sustained ventricular tachycardia (VT) or ventricular fibrillation (VF)
• Contraindication for coronary revascularization
• Prior coronary artery bypass graft
• Indication for coronary artery bypass graft surgery
• Co-morbidity with life expectancy less than 6 months
• Type 2 myocardial infarction

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite of cardiovascular death or rehospitalization for non-fatal myocardial infarction during follow-up.

Secondary Outcome Measures

Name	Time	Method
• Cardiovascular death during follow-up<br>• Rehospitalization for non-fatal myocardial infarction during follow-up<br>• All-cause death during follow-up<br>• Ischemia-driven revascularization during follow-up<br>• Rehospitalization for heart failure during follow-up<br>• Composite of all-cause death, rehospitalization for non-fatal myocardial infarction, or rehospitalization for ischemia-driven revascularization during follow-up<br>• Coronary artery bypass surgery during follow-up<br>• Quality of Life at 12 months (EQ-5D)