NL-OMON39987
已完成
4 期
icotine Replacement Therapy in the Intensive Care Unit: a randomized, controlled pilot study. - NicGoWell
Ziekenhuisvoorzieningen Gelderse Vallei0 个研究点目标入组 47 人待定
概览
- 阶段
- 4 期
- 干预措施
- 未指定
- 疾病 / 适应症
- icotine ontwenning
- 发起方
- Ziekenhuisvoorzieningen Gelderse Vallei
- 入组人数
- 47
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
Trial is onging in other countries
研究者
入排标准
入选标准
- •Any patient admitted to the intensive care unit must meet all of the following criteria to;be eligible for the study:;\- Critically ill active smoking patient;\- Being mechanically ventilated ;\- Start of study product application within 48 hours after ICU admission;\- Expected to be mechanically ventilated for more than 48 hours after start of application of the study product
排除标准
- •Any patient admitted to the intensive care unit meeting one or more of the following;criteria is not eligible for the study:;\- Patient younger than 18 years ;\- Patient or next of kin denying research authorization;\- Pregnancy;\- Breastfeeding women;\- History of chronic dementia or psychosis;\- (Acute) neurologic disease on admission, possibly confounding study objectives (TBI, stroke, ICH/SAH, seizures, meningitis, encephalitis, intracranial tumor);\- Patient receiving any form of NRT within two weeks before admission ;\- Patient not understanding Dutch;\- Patient with acute myocardial infarction;\- Patient with severe cardiac aritmia;\- Patient with unstable or deteriorating angina pectoris;\- Patient with generalized acute or chronic skin diseases interfering with NRT absorption;\- Patient with severe hearing deficiency;\- Moribund patient;\- Patient with known hypersensibility to nicotine or components of the transdermal therapeutic system;\- Patient with known hypersensibility to patches;\- Patient participating in an other study
结局指标
主要结局
未指定
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