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Clinical Trials/NL-OMON49504
NL-OMON49504
Completed
Phase 4

The effects of enoximone in acute exacerbation COPD: a pilot study - The effects of enoximone in acute exacerbation COPD: a pilot study

Rijnstate Ziekenhuis0 sites4 target enrollmentTBD
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ConditionsAcute pulmonary attackBronchospasmExacerbation COPD10024967

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Acute pulmonary attack
Sponsor
Rijnstate Ziekenhuis
Enrollment
4
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

Trial is onging in other countries

Registry
who.int
Start Date
TBD
End Date
December 21, 2021
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
Rijnstate Ziekenhuis

Eligibility Criteria

Inclusion Criteria

  • •Patients with an AE\-COPD wherefore intubation occurred within 24 hours before
  • •enrollment.

Exclusion Criteria

  • •Patients with known asthma or interstitial lung disease (ILD)
  • •Known neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS),
  • •Multiple Sclerosis (MS), Guillain\-Barre and Dementia
  • •Hypertrophic obstructive cardiomyopathy (HOCM)
  • •Severe aortic stenosis with aortic valve area \<1 cm2
  • •Known ventricular arrhythmias
  • •Severe kidney disorders with Glomerular Filtration Rate (GFR) \< 30 ml/min
  • •Severe liver insufficiency with spontaneous PT/INR \> 1\.5

Outcomes

Primary Outcomes

Not specified

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