study the effect of dexmedetomidine drug in preventing confusional state and agitation that occurs in patients undergoing brain surgery under general anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system
- Registration Number
- CTRI/2021/11/037735
- Lead Sponsor
- Institutional Review BoardChristian Medical CollegeVellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 and 2 Paediatric age group patients planned for craniotomy under general anaesthesia will be recruited for the study.
Exclusion Criteria
1)ASA 3 and above.
2)Known allergy to study drugs.
3)History of renal disease-age appropriate e-GFR criteria
4)History of liver disease.
5)Psychiatric illness
6)Heart block, known case of seizure disorder coming for seizure surgery
7)Patient refusal
8)GCS <15
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Emergence Delirium as assessed by the PAED scaleTimepoint: 7 time points,T1-at recovery,T2 after 2 hours of recovery,T3-6 hours,T4-12 hours,T5-24 hours,T6- 36 hours,T7-48 hours
- Secondary Outcome Measures
Name Time Method 1)Emergence Agitation as assessed by Watcha, Richmond�s agitation sedation scale <br/ ><br>2.Intraoperative and Postoperative haemodynamics <br/ ><br> <br/ ><br>3.Recovery characteristics <br/ ><br> <br/ ><br>4.Postoperative Analgesia <br/ ><br>Timepoint: 7 time points,T1-at recovery,T2 after 2 hours of recovery,T3-6 hours,T4-12 hours,T5-24 hours,T6- 36 hours,T7-48 hours