Impact of vitamin D status on risk of cardiovascular disease.

Phase 4

Completed

• Conditions: Cardiovascular - Coronary heart disease; Diet and Nutrition - Other diet and nutrition disorders; We are studying whether vitamin D deficiency increases cardiovascular risk

• Registration Number: ACTRN12609000584235
• Lead Sponsor: Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Healthy adults

Exclusion Criteria

Treatment with 25-hydroxy vitamin D or 1,25-dihydroxy vitamin D
Beta-blocker medication
Diabetes mellitus
Atrial fibrillation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cross-sectional study: Simple linear regression relationship between serum 25-hydroxy vitamin D levels and pulse wave velocity (PWV) and baroreceptor sensitivity (BRS).<br>Interventional study: Change in PWV and BRS.[Cross-sectional study: One timepoint only.<br>Interventional study: 2-4 weeks after second (and final) dose of vitamin D.]

Secondary Outcome Measures

Name	Time	Method
Cross-sectional study: Simple linear regression relationship between serum 25-hydroxy vitamin D levels and augmentation index (AIx).<br>Interventional study: Change in AIx.[Cross-sectional study: One timepoint only.<br>Interventional study: 2-4 weeks after second (and final) dose of vitamin D.]