A drug-drug interactions and food-effect study of S-600918 in healthy adult participants
- Conditions
- Refractory chronic cough
- Registration Number
- JPRN-jRCT2031200413
- Lead Sponsor
- agata Tsutae
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 42
Apparently healthy as determined by the investigator or subinvestigator based on medical assessment.
-Weight within the range 50 kg (inclusive) to 85 kg (exclusive), and body mass index (BMI) within the range 18.5 kg/m2 (inclusive) to 25.0 kg/m2 (inclusive).
-Capable of giving the signed ICF as described in this protocol which includes compliance with the requirements and deadlines listed in the ICF and in this protocol.
-History or presence of significantly disorders that, in the opinion of the investigator or subinvestigator, would constitute a safety concern or donfound data interaption.
-Exposure to more than 4 study drugs within 12 months prior to the first dose of study intervention.
-Previous administration of S-600918.
-Ineligibility for the study as considered by the investigator or subinvestigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maximum plasma concentration (Cmax), time to maximum plasma concentration (Tmax), area under the concentration-time curve (AUC), terminal elimination half-life (t1/2,z), and terminal elimination rate constant (lambdaz), mean residence time (MRT), apparent total clearance (CL/F), and apparent volume of distribution in the terminal elimination phase (Vz/F)
- Secondary Outcome Measures
Name Time Method