A validation study on clinical symptoms and biomarkers in patients undergoing m3 extractio

Withdrawn

• Conditions: Pain; Postextraction Pain; 10019190

• Registration Number: NL-OMON40294
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Healthy subjects with age between 18 and 45 and BMI between 20 and 27 kg/m2 at screening

Exclusion Criteria

Clinically significant acute illness within 7 days prior to study procedure.
Anti blood clotting medication
Donation of 1 or more units (approximately 450 mL) of blood or acute loss of an equivalent amount of blood within 90 days prior to study procedure.
Has received an experimental drug or used an experimental medical device within 30 days before the planned start of treatment.
Allergy to standard rescue medication Ibuprofen.
History of gastro-intestinal disturbances (gastropathy)
Psychological and/or emotional problems, which would render the informed consent invalid, or limit the ability of the subject to comply with the study requirements.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Interpatient pain response on NRS, biomarkers and genetic profile.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>