iver histolgy changes after weight loss induced by bariatric surgery
Not Applicable
Completed
- Conditions
- E66Obesity
- Registration Number
- DRKS00006023
- Lead Sponsor
- Innere Medizin I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Obesity BMI>40kg/m2 or BMI>35kg/m2 and additional disease
Exclusion Criteria
secondary cause of obesity
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in liver histology according to the classification of BRUNT - Baseline versus 10 years follow up
- Secondary Outcome Measures
Name Time Method metabolic parameters (glucose, insulin, HOMA-IR, lipid parameters etc.) - Changes baseline versus 10 years follow up
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie liver histology improvements after bariatric surgery-induced weight loss in DRKS00006023?
How does bariatric surgery compare to pharmacotherapy in reversing non-alcoholic steatohepatitis (NASH) in obese patients?
What biomarkers predict favorable liver histology outcomes following bariatric surgery in DRKS00006023 participants?
What are the long-term adverse events associated with bariatric surgery in managing E66 obesity and liver disease?
Are there combination therapies with bariatric surgery that enhance liver regeneration in NASH patients with E66 obesity?