A Clinical trial on Kuppaimeni Chooranam in the management of RATHTHA MOOLAM (BLEEDING HEMORRHOIDS)
Phase 2
- Conditions
- Health Condition 1: K640- First degree hemorrhoids
- Registration Number
- CTRI/2023/05/052275
- Lead Sponsor
- Government Siddha Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients who will be having classical symptoms of bleeding piles (1st degree Internal Hemorrhoids) i.e. constipation, Bleeding per anus, Itching in the perianal region.
2.Patients who are all willing to give blood samples at subsequent visit are involved in this study.
Exclusion Criteria
1.Patients of age below 18 years and above 60 years.
2.Patient having 2nd, 3rd degree internal haemorrhoids,Pregnancy,Fissure in ano,Fistula in ano,Diabetes mellitus,Systemic Hypertension.
Rectal Malignancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Of during and after treatment and reduction in clinical symptoms of bleeding during defecation, constipation after defecation, pruritus ani.Timepoint: 45 days
- Secondary Outcome Measures
Name Time Method 1.To evaluate the pharmacological activities of <br/ ><br>trial drug. <br/ ><br>2.Study about the prevalence of RATHA <br/ ><br>MOOLAM in relation between diet and lifestyle. <br/ ><br>3.To determine antimicrobial activity of trail drug <br/ ><br>in different solvents. <br/ ><br>4.To find out primary phytochemical analysis in <br/ ><br>trail drug. <br/ ><br>5.To evaluate proctoscopical changes in internal <br/ ><br>haemorrhoids. <br/ ><br>6.To evaluate safety profile for acute and <br/ ><br>subacute toxicity. <br/ ><br>7.To perform bio chemical analysis.Timepoint: 45 days