Simvastatin treatment inhibit monocyte chemotactic protein-1 (MCP-1) gene in endometriosis
Not Applicable
Completed
- Conditions
- EndometriosisendometriosisMCPǃImmune response
- Registration Number
- TCTR20130627003
- Lead Sponsor
- Ramathibodi hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 20
Inclusion Criteria
Diagnosed endometriosis patient and need laparoscopic surgery
willing to participate
Not on Statin medication
Never treated with GnRH agonist
Never treated with DMPA
No contraindication for simvastatin; abnormal liver function test
Exclusion Criteria
Participants have side effects from medication such as myalgia, nausea, vomiting, diarrhea
Participants deny or withdraw
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum MCP-1 8 moths ELISA
- Secondary Outcome Measures
Name Time Method endometriotic tissue MCP-1 8 months gene expression by real time PCR