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Prevention of Acute Mountain Sickness by Intermittent Hypoxia

Not Applicable
Completed
Conditions
Acute Mountain Sickness
Interventions
Other: Hypoxic Exposure
Registration Number
NCT00559832
Lead Sponsor
Heidelberg University
Brief Summary

Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective in prevention of acute mountain sickness (AMS).

The aim of this study is to investigate whether intermittent exposure to normobaric hypoxia during sleep is also effective to prevent AMS.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
75
Inclusion Criteria
  • healthy
Exclusion Criteria
  • Altitude exposure above 2000 m 8 weeks prior or during the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
HypoxiaHypoxic ExposureSleeping in normobaric hypoxia for 14 nights at altitudes from 2500 - 3300 m prior to one night at 4500 m
Primary Outcome Measures
NameTimeMethod
incidence of acute mountain sicknessduring one night at 4500 m
Secondary Outcome Measures
NameTimeMethod
Sleep qualityduring one night at altitude
ventilatory acclimatizationduring one night at altitude

Trial Locations

Locations (1)

Sports Medicine, University Hospital

🇩🇪

Heidelberg, Germany

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