Training in Hypoxia to Prevent Acute Mountain Sickness
Not Applicable
- Conditions
- Acute Mountain SicknessHealthy
- Interventions
- Other: hypoxiaOther: normoxia
- Registration Number
- NCT00886912
- Lead Sponsor
- Heidelberg University
- Brief Summary
Some studies suggest that high-altitude related illnesses - like acute mountain sickness - could be prevented by acclimatisation, reached at low altitude using training in simulated altitude. The purpose of this study is to determine whether training in hypoxia is suitable to prevent acute mountain sickness.
- Detailed Description
In a three week-period, healthy probands undergo 3 times a week a bicycle ergometer training in simulated altitude followed by 1 week passive exposure at simulated low altitude. 5 days after last exposure, a field study starts performing a rapid ascent to the Capanna Regina Margherita (4559m). Acute mountain sickness is assessed by established scoring systems.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- healthy
- non-smoker
- endurance training min. 2x/week
Exclusion Criteria
- any diseases
- previous exposure to altitudes higher than 2000m (last 6 weeks)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Hypoxia hypoxia training in simulated altitude Normoxia normoxia training under normoxic conditions
- Primary Outcome Measures
Name Time Method Incidence of acute mountain sickness after 20 hours at 4559m
- Secondary Outcome Measures
Name Time Method Severity of acute mountain sickness after 20 hours at 4559m
Trial Locations
- Locations (1)
Departement of Sports Medicine, University of Heidelberg
🇩🇪Heidelberg, Germany