Prevalence and Risk Factor of NP in Women With LUTS

Completed

• Conditions: Lower Urinary Tract Symptoms

• Registration Number: NCT04104100
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of women with lower urinary tract symptoms (LUTS). Thus, our aim is to describe the prevalence and risk factors of nocturnal polyuria in women with LUTS.

Detailed Description

Between September 2010 and January 2019, all women with LUTS visiting urogynecological department of a medical center for urodynamic evaluation were reviewed. Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for \<65 year-old women. Backward stepwise multivariable logistic regression analysis was performed using all statistical variables in the univariate logistic regression analysis. P \< 0.05 was considered as statistical significant.

Study Timeline

• Study Start: 2010-09-01
• Primary Completion: 2019-01-31
• Study Completion: 2019-01-31
• Status Verified: 2019-08
• Study First Submitted: 2019-09-24
• Study First Submitted QC: 2019-09-24
• Last Update Submitted: 2019-09-24
• Study First Posted: 2019-09-26
• Last Update Posted: 2019-09-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 3000

Inclusion Criteria

• Women with lower urinary tract symptoms
• Complete a 3-day bladder diary

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Exclusion Criteria

• <20 y/o or > 85 y/o
• Regular urethral catheterization or intermittent self-catheterization
• Urinary tract infection or chronic inflammation in the previous 2 weeks
• Bladder calculus
• Neurogenic bladder due to radical hysterectomy or injury of the central nervous system
• History of pelvic radiotherapy or a preexisting malignant pelvic tumor.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nocturnal polyuria	Between August 2007 and December 2010	Nocturnal polyuria was defined when the proportion of night-time voided volume over 24-hour voided volume was greater than 33% for ≥65 year-old women, and when the proportion of night-time voided volume over 24-hour voided volume was greater than 20% for \<65 year-old women.