Risk Factors for Recurrent Urinary Tract Infection in Children

Completed

• Conditions: Urinary Tract Infection; Pyelonephritis; Cystitis

• Registration Number: NCT00528476
• Lead Sponsor: Kaunas University of Medicine

Brief Summary

The purpose of this study is to determine clinical and urodynamic risk factors for recurrent urinary tract infection in 5-18 years old children.

Detailed Description

It is known, that in the group of young children the most common reason of recurrent UTI is anatomic abnormalities, such as vesicoureteral reflux, hydronephrosis. However, not all recurrent UTI can be explained by anatomic abnormalities. The vast majority of school age children with recurrent UTI have anatomically normal urinary tract. Recent studies discuss about the role of behavioral and functional abnormalities (inadequate fluid intake, stool retention, infrequent voiding, etc.) that can predispose recurrent urinary tract infections. Influence of some these abnormalities for recurrent UTI is controversial. Family history, behavioral and functional abnormalities which predispose to urinary tract infections in children with normal urinary tract are neglected in most protocols of urinary tract infection.

Children in this study receive a careful evaluation including complete history, voiding-drinking diary, bowel questionnaire, physical investigation, sonography, voiding cystourethrogram.

Follow up time - 1 year. Urinalysis once a month and during each episode of fever.

Study Timeline

• Study Start: 2004-11
• Study Completion: 2007-01
• Status Verified: 2007-09
• Study First Submitted: 2007-09-10
• Study First Submitted QC: 2007-09-11
• Last Update Submitted: 2007-09-11
• Study First Posted: 2007-09-12
• Last Update Posted: 2007-09-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 161

Inclusion Criteria

• 5-18 years old children, who were treated because of cystitis and pyelonephritis in Kaunas Medical University Hospital

Exclusion Criteria

• urinary tract malformations
• neurogenic bladder dysfunction
• patients, who received immunosuppressive drugs
• pregnant girls
• children with non bacterial urinary tract infection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Kaunas University of Medicine; 🇱🇹 Kaunas, Lithuania