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临床试验/NCT00528476
NCT00528476已完成不适用

Role of Clinical and Urodynamic Risk Factors for Recurrent Urinary Tract Infection in 5-18 Years Old Children

Kaunas University of Medicine1 个研究点 分布在 1 个国家目标入组 161 人开始时间: 2004年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
161
试验地点
1

研究概览

简要总结

The purpose of this study is to determine clinical and urodynamic risk factors for recurrent urinary tract infection in 5-18 years old children.

详细描述

It is known, that in the group of young children the most common reason of recurrent UTI is anatomic abnormalities, such as vesicoureteral reflux, hydronephrosis. However, not all recurrent UTI can be explained by anatomic abnormalities. The vast majority of school age children with recurrent UTI have anatomically normal urinary tract. Recent studies discuss about the role of behavioral and functional abnormalities (inadequate fluid intake, stool retention, infrequent voiding, etc.) that can predispose recurrent urinary tract infections. Influence of some these abnormalities for recurrent UTI is controversial. Family history, behavioral and functional abnormalities which predispose to urinary tract infections in children with normal urinary tract are neglected in most protocols of urinary tract infection.

Children in this study receive a careful evaluation including complete history, voiding-drinking diary, bowel questionnaire, physical investigation, sonography, voiding cystourethrogram.

Follow up time - 1 year. Urinalysis once a month and during each episode of fever.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
5 Years 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • 5-18 years old children, who were treated because of cystitis and pyelonephritis in Kaunas Medical University Hospital

排除标准

  • urinary tract malformations
  • neurogenic bladder dysfunction
  • patients, who received immunosuppressive drugs
  • pregnant girls
  • children with non bacterial urinary tract infection

研究者

申办方类型
Other

研究点 (1)

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