Verhoogt ‘scratching’ van het baarmoederslijmvlies de kans op een spontane zwangerschap in paren met onverklaarde verminderde vruchtbaarheid en een spontane kans op zwangerschap van >30%?
- Conditions
- nexplained subfertility, scratching, live birth, implantation, endometrium
- Registration Number
- NL-OMON22066
- Lead Sponsor
- MC Utrecht<br>Trial executed within the NVOG-consortium 2.0
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 792
Inclusion Criteria
1.Diagnosis of Unexplained Infertility (UEI) and a Hunault of > 30%.
2.Female age 18-43 years
Exclusion Criteria
1.History of lower abdominal or pelvic infection
2.Higher chance of intra-abdominal infection due to intestinal surgery (for for instance Crohn’s disease or colitis)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cumulative live birth rate (of which the ‘ongoing’ status should be achieved within 12 months after randomisation)
- Secondary Outcome Measures
Name Time Method -Ongoing pregnancy rate<br /><br>-Clinical pregnancy rate<br /><br>-Miscarriage rate<br /><br>-Twin birth rate<br /><br>-Time to pregnancy<br /><br>-Progression to IUI treatment<br /><br>-Progression to IVF treatment<br /><br>-Costs<br /><br>-Endometrial tissue parameters in relation to reproductive succes or failure