Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients Undergoing Caesarean Section
Phase 2
- Conditions
- Post-Dural Puncture Headache
- Interventions
- Drug: Intravenous drug
- Registration Number
- NCT05202574
- Lead Sponsor
- Minia University
- Brief Summary
Comparing dexamethasone and ondanestrone injection in ncidence of postdural puncture headache and post-partum nausea and vomiting
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
- A total of one hundred and fifty parturients in child bearing period (20-40 years), with BMI of 23-27, and ASA physical status II, who were candidate for elective caesarean section, were enrolled in this prospective randomized study.
Exclusion criteria
Exclusion Criteria
1 - Lady refusal to participate. 2. All pregnant women candidate for emergency caesarean section elligible for general anaesthesia (GA).
3.presence of any contraindications of dexamethasone (as DM and uncontrolled infection ) or any contraindication of ondansetron (as prolonged QT interval 6. Presence of cardiac, respiratory, hepatic, renal and mental diseases. 7. Coagulopathy, or any contraindication to spinal anaesthesia. 8. Presence of complicated pregnancies (such as pregnancy induced hypertension, placenta previa or eclmpsia).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description ondanestrone Intravenous drug - dexamethasone Intravenous drug - control group Intravenous drug -
- Primary Outcome Measures
Name Time Method incidence of post-dural puncture hedache 24 hours post-partum
- Secondary Outcome Measures
Name Time Method incidence of post-partum nausea and vomiting 24 hours post-partum
Trial Locations
- Locations (1)
Mina Raouf
🇪🇬ALMinya, Minia, Egypt