Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery

Phase 4

Completed

• Conditions: Vomiting; Nausea
• Interventions: Drug: Ondansetron; Drug: Dexamethasone

• Registration Number: NCT01007500
• Lead Sponsor: Yonsei University

Brief Summary

The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2009-11-03
• Study First Submitted QC: 2009-11-03
• Study First Posted: 2009-11-04
• Primary Completion: 2010-07
• Study Completion: 2010-09
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-29
• Last Update Posted: 2016-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 123

Inclusion Criteria

• Patients undergoing video-assisted thoracoscopic surgery
• Age 20-75
• American Society of Anesthesiologists physical status classification I or II

Exclusion Criteria

• Antiemetic within 24 hrs
• Taking Steroids, Opioids within 1 week
• Active drug or alcohol abuse
• GI motility disorder, severe renal/ hepatic disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group Ondansetron	Ondansetron	-
Group Dexamethasone	Dexamethasone	-

Primary Outcome Measures

Name	Time	Method
Incidence of postoperative nausea and vomiting	within 48 hrs after surgery

Trial Locations

Locations (1)

Severance Hospital, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of