Cortical Organization in Allogeneic Transplants or Heterotopic Hand Replants
- Conditions
- Hand ReplantHand Transplant
- Registration Number
- NCT01618682
- Lead Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
- Brief Summary
The investigators hope to gain insights into the functional organization of the human cerebral cortex in response to upper limb amputation and surgical interventions including hand replantation and hand transplantation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- between 18-70 yrs old
- undergone successful allogeneic transplantation of one or both hands OR undergone successful reattachment of one or both hands OR will have experienced surgical repair of one or more severed nerves (ulnar, medial, radial, digital in the upper limb
- must speak English
Exclusion Criteria
- younger than 18 years or older than 70 years
- not undergone a replant or transplant
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ultrasound Biomicroscopy Up to 12 months We will scan the cross section of the medial nerve at the pisiform bone level to determine the level of CTS with Ultrasound Biomicroscopy machine. This device is not approved for clinical decisions, only used for research purposes.
- Secondary Outcome Measures
Name Time Method DASH Questionnaire Up to 12 months Subjects will complete the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire.
Pinch Strength Up to 12 months Grip Strength Up to 12 months
Trial Locations
- Locations (1)
Christine M. Kleinert Insitute of Hand and Microsurgery
🇺🇸Louisville, Kentucky, United States