Effects of Vibration Training on Exercise Capacity in COPD-patients

Not Applicable

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Other: whole body vibration training

• Registration Number: NCT01380639
• Lead Sponsor: Schön Klinik Berchtesgadener Land

Brief Summary

The aim of this study is to investigate the exercise capacity in COPD-patients performing a vibration training additional to a standard three-week rehabilitation program in comparison to patients performing merely a rehabilitation program.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09
• Primary Completion: 2011-04
• Study Completion: 2011-04
• Study First Submitted: 2011-04-01
• Study First Submitted QC: 2011-06-23
• Study First Posted: 2011-06-27
• Results First Submitted: 2013-09-27
• Results First Submitted QC: 2013-09-27
• Results First Posted: 2013-11-28
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-10
• Last Update Posted: 2019-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• Chronic obstructive pulmonary disease III/IV

Exclusion Criteria

• Severe exacerbations in the last 4 weeks prior to begin of study (definition of exacerbation: symptoms on more than 3 days with a relevant change in drug therapy (cortisone, antibiotics))
• Severe disease other than COPD, that could influence the results of the study
• Abuse of alcohol or drugs
• Simultaneously participation in another study
• Tachypnea (>30/min)
• Severe exacerbation during rehabilitation
• Cardiac insufficiency (NYHA IV)
• Myocardial infarction during the last 6 weeks
• Mental-health problem
• Pregnancy
• Known HIV-infection
• Slipped disk
• Acute discopathy
• Acute thrombosis
• Implants in trained regions of the body (lower extremities)
• Acute inflammation of the locomotor system, active arthrosis or rheumatoid arthritis
• Acute tendinopathy in trained regions of the body
• Acute hernia
• Fresh fractures, wounds or scars in trained regions of the body
• Gallstones or stones in the urinary tract collection system

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Rehabilitation with vibration training	whole body vibration training	-

Primary Outcome Measures

Name	Time	Method
6-Minute-Walking-Distance	day 1, day 19	Change in 6-minute-walking-distance from baseline to day 19

Secondary Outcome Measures

Name	Time	Method
Isometric Maximum Handgrip Force	day 1, day 19	change in isometric max. handgrip force from baseline to day 19
Arterial Blood Gas	day 1
Brain Natruretic Peptide (BNP)	day 1, day 19	change in BNP from baseline to day 19
BODE-Score	day 1, day 19	Change in Bode-Score from baseline to day 19
Body Composition	day 1 and 19	Change in body composition from baseline to day 19
Lung Function	day 1

Trial Locations

Locations (1)

Schön Klinikum Berchtesgadener Land; 🇩🇪 Schönau am Königssee, Germany