Comprehensive study of brain stiffness and brain viscoelasticity measured by tactile biosensor over the scalp
- Conditions
- inpatient who underwent decompressive craniectomy
- Registration Number
- JPRN-UMIN000002233
- Lead Sponsor
- Department of Neurosurgery Shimane University Faculty of Medicine
- Brief Summary
Background: Decompressive craniectomy is undertaken for relief of brain herniation caused by acute brain swelling. Brain stiffness can be estimated by palpating the decompressive cranial defect and can provide some relatively subjective information to the neurosurgeon to help guide care. The goal of the present study was to objectively evaluate transcutaneous stiffness of the cranial defect using a tactile resonance sensor and to describe the values in patients with a decompressive window in order to characterize the clinical association between brain edema and stiffness. Methods: Data were prospectively collected from 13 of 37 patients who underwent a decompressive craniectomy in our hospital during a 5-year period. Transcutaneous stiffness was measured as change in frequency and as elastic modulus. Results: Stiffness variables of the decompressive site were measured without any adverse effect and subsequent calculations revealed change in frequency =101.71/36.42 Hz, and shear elastic modulus =1.99/1.11 kPa. Conclusions: The elasticity of stiffness of a decompressive site correlated with brain edema, cisternal cerebrospinal fluid pressure, and brain shift, all of which are related to acute brain edema.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
posterior fossa decompression, internal decompression of brain cortex, infection, and hemorrhagic tendency
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We measured the correlation between degree of palpation and viscoelastic value by tactile biosensor from immediate postoperative day to the day of cranioplasty.
- Secondary Outcome Measures
Name Time Method We evaluated neurology and the brain swelling degree of head CT