The Sensitivity and Specificity of Electrospun Containing Toluidine blue in the Detection of Oral Potentially Malignant Disorders
Phase 4
- Conditions
- Patients who are suspected of having oral potentially malignant disorders or non-healing ulcer more than 2 weeks without any identifiable cause requiring biopsyElectrospun, Oral potentially malignant disorders, Toluidine blue, Sensitivity, Specificity
- Registration Number
- TCTR20220712007
- Lead Sponsor
- Royal College of Dental Surgeons
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
1.Male or female subjects age > 20 years old
2.Patients who are suspected of having oral potentially malignant disorders
3.Patients with non-healing ulcer more than 2 weeks without any identifiable cause
4.Patients who can be followed up
5.Patients who give their consent for the study
Exclusion Criteria
1.Patients with severe systemic diseases that interfere with or contraindication to the biopsy procedure
2.Patients with the presence of obvious invasive carcinomas
3.Patients who abandoned treatment
4.Patients who refuse the study
5.Patients who are allergic to toluidine blue, acetic acid, polyvinylpyrrolidone or local anesthetic agents
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Staining of oral potentially malignant disorders by the use of electrospun containing toluidine blue Time of treatment Visual examination
- Secondary Outcome Measures
Name Time Method Histopathological diagnosis Time of treatment Histopathological evaluation