The effect of viscosity on the rate of gastric emptying
Completed
- Conditions
- obesitas10003018
- Registration Number
- NL-OMON34934
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
*Apparently healthy, self reported
*Young adult males: 18-30 year
*Normal weight: BMI 18.5-25 kg/m2
*Used to eating breakfast (> 5 times per week)
*
Exclusion Criteria
*Loss of appetite
*Weight change of >5kg during the last 2 months
*Being on a weight loss diet
*On a prescribed diet that interferes with the study foods
*Bowel or stomach disorder
*Diabetes or thyroid disorder
*Food intolerance or allergy for foods that are provided during the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study outcome is gastric emptying (and the variation in that<br /><br>measurement). Gastric emptying will be measured with a non-invasive breath<br /><br>test. The subject will come in fasting state to the research centre and ingest<br /><br>the test product which is labelled with 13C. The test foods consist of 2<br /><br>chocolate flavoured milk products, differing in viscosity. Breath samples will<br /><br>be collected before consumption of the food and at 15 minute intervals during 3<br /><br>hours. Breath samples will be analyzed on concentration of 13C. 13C recovery<br /><br>(T1/2 and Tlag) will be used as a measure for gastric emptying. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Appetite and wellbeing ratings will be measured during the test by means of<br /><br>Visual Analogue Scales.</p><br>