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Effect of Anti-inflammatory Diet in Rheumatoid Arthritis

Not Applicable
Recruiting
Conditions
Rheumatoid Arthritis
Interventions
Other: Diet 1
Other: Diet 2
Registration Number
NCT04748809
Lead Sponsor
University of California, San Diego
Brief Summary

In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
124
Inclusion Criteria
  • Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits.
Exclusion Criteria
  • Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study.
  • Food allergies
  • Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretation of the results

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm_1Diet 1Anti-inflammatory diet 1
Arm_2Diet 2Anti-Inflammatory diet 2
Primary Outcome Measures
NameTimeMethod
Decrease of more than 5 points in Clinical Disease Activity Index3 months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UCSD

🇺🇸

La Jolla, California, United States

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