nblinded randomized control trial on Prophylactic Antibiotic Use in Gustilo II Open Tibia Fractures at Kenyatta National Hospital, Kenya

Not Applicable

• Conditions: Musculoskeletal Diseases; Open fractures

• Registration Number: PACTR201606001689132
• Lead Sponsor: JOSHUA N ONDARI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 84

Inclusion Criteria

¿Patients with isolated Gustilo grade II open tibial fractures.
¿Patients aged between 18 and 80 years. Pediatric patients were excluded because of fixed dosage regimen in the study protocol.

Exclusion Criteria

¿Gustilo II open tibial fractures whose wounds could not be closed primarily after debridement
¿Fractures that were not debrided within 24 hours of injury
¿Non ¿ traumatic open tibia fractures such as pathological fractures
¿Cigarette smokers
¿Patient with diabetes mellitus, HIV/AIDS, psychosis or chronic renal failure
¿Patients on corticosteroids or chemotherapy
¿Patients referred from other medical facilities where they had already received any form of treatment
¿Hemodynamically unstable patients
¿Patients who refused to give consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
INFECTIO

Secondary Outcome Measures

Name	Time	Method
Effect of duration to antibiotic administration on infectionj rate