Tissue- and reflex torque through ramp-and-hold ankle rotations: understanding and quantifying spasticity in cerebral palsy

Completed

• Conditions: Cerebral palsy; spastic paresis; 10028037

• Registration Number: NL-OMON34272
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

- Diagnosis of spastic cerebral palsy.
- Age between 6 and 18 years.
- Gross Motor Function Scale (GMFCS, see appendix) I, II or III.

Exclusion Criteria

Concomitant neurological diseases.
Concomitant orthopedic problems of the lower extremities.
Casting or Botulinum toxin A injections within the previous 4 months.
Orthopedic surgery of the lower leg; orthopedic surgery in other body parts within the previous 12 months.
Tendon and tissue surgery at the lower leg.
Previous Selective Dorsal Rhizotomy or intrathecal Baclofen treatment.
Inability to take prescribed test condition (hip 70°, knee 20° and 90°).
Severe cognitive or language deficits or disturbed behavior interfering with the comprehension of instructions required to participate in the study.
GMFCS IV or V (to exclude disuse or muscle atrophy).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Ankle stiffness (Nm/rad), viscosity (Nms/rad) and reflex activity (Nm/rad)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>SPAT and AS scores</p><br>