Clinical efficacy, safety and mechanism of Yiqi Shengjin powder on blood pressure in patients with abnormal glucose metabolism and hypertensio

Phase 1

• Conditions: abnormal glucose metabolism and hypertension

• Registration Number: ITMCTR2200006446
• Lead Sponsor: Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

1) The subject or responsible guardian shall sign the informed consent; 2) Aged 18-75 years; 3) In patients with impaired fasting glucose, abnormal glucose tolerance or type 2 diabetes mellitus(HbA1C<8% in the past 2 weeks without taking or taking western antidiabetic drugs); 4) Patients with grade 1-2 essential hypertension; 5) TCM syndromes accord with Qi and Yin deficiency syndrome

Exclusion Criteria

1) Pregnant and lactation patients;
2) Malignant tumors or blood diseases;
3) Patients who are critically ill or not yet stable in the acute phase, have consciousness disorders, severe cognitive dysfunction or serious mental diseases;
4) A history of alcohol and drug abuse;
5) Patients with acute myocardial infarction, unstable angina pectoris, large aneurysm or dissecting aneurysm, NYHA class III-IV heart failure, malignant arrhythmia, and other severe liver, kidney, hematologic, cerebrovascular diseases and severe osteoporosis within 6 months (Note: Liver dysfunction is to point to alanine aminotransferase or aspartate aminotransferase value is greater than 2 times the upper limit of normal; Renal insufficiency refers to a serum creatinine value greater than 2 times the upper limit of normal);

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The total effective rate of lowering blood pressure;

Secondary Outcome Measures

Name	Time	Method
Oxidative stress index;Lipid metabolism index;24h ambulatory blood pressure monitoring index;Glucose metabolism index;Vascular injury detection index;TCM syndrome integration;Aging indicators;