A study to look at the protective effect of two toothpastes against tooth erosio

Not Applicable

Completed

• Conditions: Enamel erosion; Oral Health

• Registration Number: ISRCTN55537791
• Lead Sponsor: Proctor & Gamble Technical Centres Ltd (UK)

Brief Summary

2019 results in https://www.ncbi.nlm.nih.gov/pubmed/30556372 (added 07/04/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-27
• Study Completion: 2016-07-22
• Last Update Posted: 27 April 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Provide written informed consent to participate in the study, and receive a copy of the signed consent form
2. Agree not to participate in any other oral/dental product studies during the course of the study
3. Agree to delay any elective dentistry (including dental prophylaxis) until the study has been completed
4. Agree to refrain from the use of any non-study dentifrice or other oral hygiene products for the duration of the study
5. Agree to return for all scheduled visits and follow study procedures
6. Be at least 18 years of age
7. Agree to refrain from taking an acidic medication (pH <5.3) during the course of the study
8. Be in good general health, as determined by the Investigator/designee based on a review of the health history/update for participation in the study

Exclusion Criteria

1. Have a susceptibility to acid regurgitation
2. Have recurrent or regular aphthous ulcers
3. Have dental erosion or a previous history of being susceptible to high dental erosion after drinking sports drinks or juices
4. Have excessive gingival inflammation
5. Have severe periodontal disease, as characterized by purulent exudate, generalized mobility, and/or severe recession
6. Have any pre-existing oral or medical condition that the examiner determines may place the subject at increased health risk from study participation
7. Have unremovable mouth or tongue jewelery
8. Any subject who in the opinion of the investigator (or medically qualified designee) should not participate in the study
9. Are personnel – an employee of the Sponsor, member of the study site or family relative

Study & Design

• Study Type: Interventional
• Study Design: Not specified